missing translation for 'onlineSavingsMsg'
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Invitrogen™ Human UBXN6 (aa 76-154) Control Fragment Recombinant Protein
Description
Highest antigen sequence indentity to the following orthologs: Mouse (78%), Rat (78%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59511 (PA5-59511. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
May negatively regulate the ATPase activity of VCP, an ATP-driven segregase that associates with different cofactors to control a wide variety of cellular processes (PubMed:26475856). As a cofactor of VCP, it may play a role in the transport of CAV1 to lysosomes for degradation (PubMed:21822278, PubMed:23335559). It may also play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins (PubMed:19275885). Together with VCP and other cofactors, it may play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes (PubMed:27753622). [UniProt]
Specifications
Specifications
| Accession Number | Q9BZV1 |
| Concentration | ≥5.0 mg/mL |
| For Use With (Application) | Blocking Assay, Control |
| Formulation | 1 M urea, PBS with no preservative; pH 7.4 |
| Gene ID (Entrez) | 80700 |
| Name | Human UBXN6 (aa 76-154) Control Fragment |
| Quantity | 100 μL |
| Regulatory Status | RUO |
| Gene Alias | 1200008L11Rik; 2210415J11Rik; AU040909; CTB-50L17.16; UBX domain containing 1; UBX domain protein 6; UBX domain-containing 1; UBX domain-containing 2; UBX domain-containing protein 1; UBX domain-containing protein 6; UBXD1; Ubxdc2; Ubxn6 |
| Common Name | UBXN6 |
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