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Invitrogen™ Human UBXN6 (aa 76-154) Control Fragment Recombinant Protein

Catalog No. RP99154
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100 μL
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RP99154 100 μL
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Catalog No. RP99154 Supplier Invitrogen™ Supplier No. RP99154
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Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (78%), Rat (78%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59511 (PA5-59511. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

May negatively regulate the ATPase activity of VCP, an ATP-driven segregase that associates with different cofactors to control a wide variety of cellular processes (PubMed:26475856). As a cofactor of VCP, it may play a role in the transport of CAV1 to lysosomes for degradation (PubMed:21822278, PubMed:23335559). It may also play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins (PubMed:19275885). Together with VCP and other cofactors, it may play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes (PubMed:27753622). [UniProt]

Specifications

Accession Number Q9BZV1
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 80700
Name Human UBXN6 (aa 76-154) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 1200008L11Rik; 2210415J11Rik; AU040909; CTB-50L17.16; UBX domain containing 1; UBX domain protein 6; UBX domain-containing 1; UBX domain-containing 2; UBX domain-containing protein 1; UBX domain-containing protein 6; UBXD1; Ubxdc2; Ubxn6
Common Name UBXN6
Gene Symbol UBXN6
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence QDTIRNQVRKELQAEATVSGSPEAPGTNVVSEPREEGSAHLAVPGVYFTCPLTGATLRKDQRDACIKEAILLHFSTDPV
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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