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Invitrogen™ Human TrkA ELISA Kit
Description
Human TrkA quantitates human TrkA in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human TrkA.
NTRK1 (TRKA) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. TrkA is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of TrkA leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in TrkA have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.
Specifications
Specifications
| Accession Number | C80751; DKFZp781I14186; EC 2.7.10.1; gp140trk; high affinity nerve growth factor receptor; kinase TrkA; MTC; neurotrophic receptor tyrosine kinase 1; Neurotrophic tyrosine kinase receptor type 1; neurotrophic tyrosine kinase, receptor, type 1; Ntrk1; Oncogene TRK; p140-TrkA; slow nerve growth factor receptor; Tkr; trk; TRK1; TRK1-transforming tyrosine kinase protein; TRKA; trk-A; TrkA neurotrophin receptor; trkA proto-oncogene receptor; tropomyosin-related kinase A; Tyrosine kinase receptor; Tyrosine kinase receptor A |
| Assay Range | 2 to 500 ng/mL |
| Assay Sensitivity | 2 ng/mL |
| Conjugate | HRP |
| Product Type | ELISA |
| Sample Type | Plasma, Serum, Supernatant |
| For Use With (Equipment) | Colorimetric Microplate Reader |
| Gene ID (Entrez) | 4914 |
| Gene Symbol | Ntrk1 |
| Interassay CV | <12% |
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