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Invitrogen™ Human TPO ELISA Development Kit (ABTS), PeproTech®

Catalog No. 900K44K
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10 x 96 Tests
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900K44K 10 x 96 Tests
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Catalog No. 900K44K Supplier Invitrogen™ Supplier No. 900K44K

Description

ELISA

Thrombopoietin (TPO, THPO, MPL ligand, megakaryocyte colony-stimulating factor) is responsible for the generation of platelets through its action on hematopoietic cells committed to the megakaryocyte lineage. Binding of thrombopoietin to its receptor, MPL (CD110), initiates a signaling cascade via JAK/STAT, MAPK, and PI3K/AKT signaling pathways that leads to the proliferation and differentiation of megakaryocytes and, ultimately, to the production of platelets (thrombopoiesis). Thrombopoietin is constitutively produced by the liver and has a predicted molecular weight of 38 kDa.

Specifications

Accession Number P40225
Assay Range Lot-specific
Assay Sensitivity Lot-specific
Conjugate HRP
Product Type ELISA
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 7066
Gene Symbol THPO
Kit Contents Capture Antibody, Detection Antibody, Protein Standard, HRP-conjugate
Label or Dye HRP
Quantity 10 x 96 Tests
Regulatory Status RUO
Storage Requirements Refer to product documentation for component specific storage temperature.
Target Thrombopoietin
Test Time 1 hrs 45 mins
Total Assay Time 24 hrs 30 mins
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