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Invitrogen™ Human TOMM20L (aa 93-150) Control Fragment Recombinant Protein

Catalog No. RP99997
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100 μL
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Catalog No. Quantity
RP99997 100 μL
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Catalog No. RP99997 Supplier Invitrogen™ Supplier No. RP99997

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (66%), Rat (66%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60889. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The TOMM20L gene encodes a protein that is highly related to the translocase of outer mitochondria membrane 20 homolog (TOMM20), which plays a crucial role in the import of mitochondrial preproteins. TOMM20L, likely a paralog or isoform of TOMM20, shares functional similarities and contributes to the complex processes facilitating protein translocation across the outer mitochondrial membrane. This gene's product is integral to the translocase of the outer mitochondrial membrane (TOM) complex, which is essential for maintaining mitochondrial function and biogenesis. TOMM20L assists in the recognition and import of cytosolic precursor proteins into the mitochondria, influencing mitochondrial assembly and function. Although the specific functions of TOMM20L compared to TOMM20 require further elucidation, it is presumed to modulate mitochondrial dynamics and physiology. Alterations in TOMM20L expression could impact mitochondrial efficiency and are relevant in conditions related to energy metabolism and mitochondrial disorders.

Specifications

Accession Number Q6UXN7
Concentration ≥5.0 mg/mL
For Use With (Application) Neutralization, Control
Formulation PBS, 1M urea with no preservative; pH 7.4
Gene ID (Entrez) 387990
Name Human TOMM20L (aa 93-150) Control Fragment
pH Range 7.4
Purification Method Purified
Quantity 100 μL
Storage Requirements -20°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias TOMM20L; TOMM20-like protein 1; translocase of outer mitochondrial membrane 20 homolog (yeast)-like; translocase of outer mitochondrial membrane 20 homolog type I; translocase of outer mitochondrial membrane 20 like; UNQ9438; UNQ9438/PRO34772
Common Name TOMM20L
Gene Symbol TOMM20L
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence GIQHLGNALLVCEQPRELLKVFKHTLPPKVFEMLLHKIPLICQQFEADMNEQDCLEDD
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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