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  5. Invitrogen™ Human SOX17 ELISA Kit

Invitrogen™ Human SOX17 ELISA Kit

Catalog No. EH434RBX5
Encompass
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5 x 96 Tests
96 Tests
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EH434RBX5 5 x 96 Tests
EH434RB 96 Tests
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Description

ELISA

Human SOX17 quantitates human SOX17 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human SOX17.

SOX17 (transcription factor SOX-17) belongs to the SRY-related HMB box family of transcription factors. It acts as a transcription regulator that binds target promoter DNA and bends the DNA. It binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-3'. SOX17 modulates transcriptional regulation via WNT3A and inhibits Wnt signaling. It promotes degradation of activated CTNNB1. SOX17 plays an essential role in the regulation of embryonic development and is required for normal looping of the embryonic hear tube and for normal development of the definitive gut endoderm. Mutations in the gene can result in vesicoureteral reflux.

Specifications

Accession Number HMG transcription factor SOX17; SOX17; Sox-17; SRY (sex determining region Y)-box 17; SRY box 17; SRY-box 17; SRY-box containing gene 17; SRY-box transcription factor 17; SRY-related HMG-box transcription factor SOX17; transcription factor SOX-17; VUR3
Assay Range 0.03 to 25 ng/mL
Assay Sensitivity 0.03 ng/mL
Conjugate HRP
Product Type ELISA
Sample Type Plasma, Serum, Supernatant
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 64321
Gene Symbol SOX17
Interassay CV <12%
Intraassay CV <10
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
Label or Dye HRP
Quantity 5 x 96 Tests
Regulatory Status RUO
Sample Volume Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
Storage Requirements 2°C to 8°C
Target SOX17
Test Time 1 hrs 20 mins
Total Assay Time 4 hrs 45 mins
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