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  5. Invitrogen™ Human Sortilin ELISA Kit

Invitrogen™ Human Sortilin ELISA Kit

Catalog No. EH433RBX5
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5 x 96 Tests
96 Tests
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EH433RBX5 5 x 96 Tests
EH433RB 96 Tests
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Description

ELISA

Human Sortilin quantitates human Sortilin in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Sortilin.

Sortilin functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Sortilin is required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). It is also required for protein transport from the Golgi apparatus to the endosomes. Sortilin promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also, Sortilin acts as a receptor for neurotensin.

Specifications

Accession Number 100 kDa NT receptor; 2900053A11Rik; AI852375; glycoprotein 110; glycoprotein 95; Gp110; Gp95; LDLCQ6; mNTR3; neurotensin receptor 3; NT3; NTR3; Nts3; Ntsr3; Sort1; Sortilin; sortilin 1
Assay Range 0.819 to 200 ng/mL
Assay Sensitivity 0.81 ng/mL
Conjugate HRP
Product Type ELISA
Sample Type Plasma, Serum, Supernatant
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 6272
Gene Symbol Sort1
Interassay CV <12%
Intraassay CV <10
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
Label or Dye HRP
Quantity 5 x 96 Tests
Regulatory Status RUO
Sample Volume Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
Storage Requirements 2°C to 8°C
Target Sortilin
Test Time 1 hrs 20 mins
Total Assay Time 4 hrs 45 mins
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