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Invitrogen™ Human RFX1 (aa 159-245) Control Fragment Recombinant Protein
Description
Highest antigen sequence indentity to the following orthologs: Mouse (82%), Rat (82%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-61809 (PA5-61809. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X2, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with RFX family members X2, X3, and X5, but not with X4. This protein binds to the X-boxes of MHC class II genes and is essential for their expression. Also, it can bind to an inverted repeat that is required for expression of hepatitis B virus genes.
Specifications
Specifications
| Accession Number | P22670 |
| Concentration | ≥5.0 mg/mL |
| For Use With (Application) | Blocking Assay, Control |
| Formulation | 1 M urea, PBS with no preservative; pH 7.4 |
| Gene ID (Entrez) | 5989 |
| Name | Human RFX1 (aa 159-245) Control Fragment |
| Quantity | 100 μL |
| Regulatory Status | RUO |
| Gene Alias | AI047719; AI385641; EFC; EF-C; Enhancer factor C; MHC class II regulatory factor RFX; MHC class II regulatory factor RFX1; Regulatory factor x 1; regulatory factor X, 1 (influences HLA class II expression); regulatory factor X1; RFX; RFX1; trans-acting regulatory factor 1; transcription factor RFX1; vregulatory factor X, 1 (influences HLA class II expression) |
| Common Name | RFX1 |
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