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Invitrogen™ Human Ret ELISA Kit
Description
Human Ret quantitates human Ret in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Ret.
The receptor tyrosine kinase RET is a member of the cadherin superfamily. RET plays a crucial role in neural crest development, and can undergo oncogenic activation by cytogenetic rearrangement. RET transduce signals for cell growth and differentiation. Mutations in the RET gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for the RET gene. Additional transcript variants have been described for RET but their biological validity has not been confirmed.
Specifications
Specifications
| Accession Number | Cadherin family member 12; cadherin-related family member 16; CDHF12; CDHR16; CG1061; CG14396; CG14396 gene product from transcript CG14396-RA; CG14396-PA; CG14396-PB; CG14396-PC; c-Ret; CU x 1/RET fusion; Dmel\CG14396; Dmel |
| Assay Range | 0.61 to 150 ng/mL |
| Assay Sensitivity | 0.61 ng/mL |
| Conjugate | HRP |
| Product Type | ELISA |
| Sample Type | Plasma, Serum, Supernatant |
| For Use With (Equipment) | Colorimetric Microplate Reader |
| Gene ID (Entrez) | 5979 |
| Gene Symbol | RET |
| Interassay CV | <12% |
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