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Invitrogen™ Human PKP1 (aa 663-747) Control Fragment Recombinant Protein
Description
Highest antigen sequence indentity to the following orthologs: Mouse (84%), Rat (84%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-82958 (PA5-82958. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].
Specifications
Specifications
| Accession Number | Q13835 |
| Concentration | ≥5.0 mg/mL |
| For Use With (Application) | Blocking Assay, Control |
| Formulation | 1 M urea, PBS with no preservative; pH 7.4 |
| Gene ID (Entrez) | 5317 |
| Name | Human PKP1 (aa 663-747) Control Fragment |
| Quantity | 100 μL |
| Gene Alias | AI528551; armadillo; B6P; band 6; band 6 polypeptide B6P; band 6 protein; Band-6 protein; MGC138829; Pkp1; plakophilin; plakophilin 1; plakophilin 1 (ectodermal dysplasia/skin fragility syndrome); plakophilin-1 |
| Common Name | PKP1 |
| Gene Symbol | PKP1 |
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