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Invitrogen™ Human PKC mu (aa 849-908) Control Fragment Recombinant Protein
Description
Highest antigen sequence indentity to the following orthologs: Mouse (83%), Rat (83%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-83107 (PA5-83107. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The PKC family of serine/threonine kinases, including PRKCN (PKD3), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent. PKC mu activation is dependent on the phosphorylation of two activation loop sites, Ser744 and Ser748, via a PKC-dependent signaling pathway.
Specifications
Specifications
| Accession Number | O94806, Q15139, Q9BZL6 |
| Concentration | ≥5.0 mg/mL |
| For Use With (Application) | Blocking Assay, Control |
| Formulation | 1 M urea, PBS with no preservative; pH 7.4 |
| Gene ID (Entrez) | 23683, 25865, 5587 |
| Name | Human PKC mu (aa 849-908) Control Fragment |
| Quantity | 100 μL |
| Regulatory Status | RUO |
| Gene Alias | 4930557O20Rik; 5730497N19Rik; AI325941; DKFZP586E0820; EPK2; HSPC187; nPKC-D1; nPKC-D2; nPKC-mu; nPKC-nu; PKC mu; PKC nu; PKC u; PKC v; Pkcm; PKCmu; PKC-MU; Pkcnu; PKC-NU; PKCu; PKC-u; PKCv; PKC-v; Pkd; PKD1; PKD2; PKD3; Prkcm; PRKCN; Prkd1; PRKD2; PRKD3; Protein kinase C mu type; protein kinase C nu type; protein kinase C, mu; protein kinase C, nu; protein kinase D; protein kinase D1; protein kinase D2; protein kinase D3; protein kinase EPK2; RGD1308054; Serine/threonine-protein kinase D1; serine/threonine-protein kinase D2; Serine/threonine-protein kinase D3 |
| Common Name | PKC mu |
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