missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Gibco™ Human Noggin Recombinant Protein, PeproTech® 
Recombinant Protein
$132.00 - $6,016.64
Specifications
| Accession Number | Q13253 |
|---|---|
| For Use With (Application) | Functional Assay |
| Formulation | protein with no preservative |
| Gene ID (Entrez) | 9241 |
| Name | Human Noggin |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|
12010C100UG
|
Gibco™
LS12010C100UG |
100 μg |
N/A
|
|
|||||
|
12010C1MG
|
Gibco™
12010C1MG |
2 x 500 μg |
N/A
|
|
|||||
|
12-010-C01M
|
Gibco™
12010C01M |
2 x 500 μg |
N/A
|
|
|||||
|
12010C20UG
|
Gibco™
LS12010C20UG |
20 μg |
N/A
|
|
|||||
|
12010C250UG
|
Gibco™
LS12010C250UG |
250 μg |
N/A
|
|
|||||
|
12010C500UG
|
Gibco™
LS12010C500UG |
500 μg |
N/A
|
|
|||||
|
12010C50UG
|
Gibco™
LS12010C50UG |
50 μg |
N/A
|
|
|||||
|
12010C5UG
|
Gibco™
LS12010C5UG |
5 μg |
N/A
|
|
|||||
Description
120-10C-1MG will be provided as 2 x 500 μg (120-10C-500UG). Recombinant Human Noggin is a 46 kDa disulfide-linked homodimer consisting of two 205 amino acid polypeptide chains. Monomeric glycosylated noggin migrates at an apparent molecular weight of approximately 28.0-33.0 kDa by SDS PAGE analysis under reducing conditions. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin; and 2) Noggin, which is a bone morphogenetic protein inhibitor. Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.Specifications
| Q13253 | |
| protein with no preservative | |
| Human Noggin | |
| RUO | |
| NOG | |
| Recombinant | |
| Lyophilized |
| Functional Assay | |
| 9241 | |
| HEK293 cells | |
| NOG; Noggin; Noggin precursor; noggin; LOW QUALITY PROTEIN: noggin; SYM1; symphalangism 1 (proximal); SYNS1; SYNS1A | |
| Unconjugated | |
| QHYLHIRPAP SDNLPLVDLI EHPDPIFDPK EKDLNETLLR SLLGGHYDPG FMATSPPEDR PGGGGGAAGG AEDLAELDQL LRQRPSGAMP SEIKGLEFSE GLAQGKKQRL SKKLRRKLQM WLWSQTFCPV LYAWNDLGSR FWPRYVKVGS CFSKRSCSVP EGMVCKPSKS VHLTVLRWRC QRRGGQRCGW IPIQYPIISE CKCSC | |
| ≥ 95% by SDS-PAGE gel and HPLC analyses. |