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Invitrogen™ Human NCoR1 Control Fragment Recombinant Protein

Catalog No. RP104767
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100 μL
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RP104767 100 μL
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Catalog No. RP104767 Supplier Invitrogen™ Supplier No. RP104767

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (92%), Rat (92%). This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.

Specifications

Accession Number O75376
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 9611
Name Human NCoR1 Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 5730405M06Rik; A230020K14Rik; h KIAA1047; hCIT529I10; hN-CoR; KIAA1047; MGC104216; mKIAA1047; NCoR; N-CoR; N-Cor/SMRT corepressor Rip13; N-Cor/SMRT corepressor, Rip13; NCOR1; N-CoR1; nuclear receptor corepressor; nuclear receptor corepressor 1; nuclear receptor co-repressor 1; PPP1R109; protein phosphatase 1, regulatory subunit 109; retinoid x receptor interacting protein 13; retinoid x receptor-interacting protein 13; RIP13; Rxrip13; thyroid hormone- and retinoic acid receptor-associated corepressor 1; TRAC1
Common Name NCoR1
Gene Symbol Ncor1
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence MSSSGYPPNQGAFSTEQSHYPPHSV
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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