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Invitrogen™ Human LPXN (aa 2-50) Control Fragment Recombinant Protein

Catalog No. RP105187
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100 μL
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RP105187 100 μL
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Catalog No. RP105187 Supplier Invitrogen™ Supplier No. RP105187
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Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (61%), Rat (61%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66394 (PA5-66394. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Specifications

Accession Number O60711
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 9404
Name Human LPXN (aa 2-50) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 4933402K05Rik; A530083L21Rik; AV278559; LDLP; LDPL; Leupaxin; LPXN
Common Name Leupaxin
Gene Symbol LPXN
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence EELDALLEELERSTLQDSDEYSNPAPLPLDQHSRKETNLDETSEILSIQ
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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