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Invitrogen™ Human L1CAM ELISA Kit
Description
Human L1CAM quantitates human L1CAM in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human L1CAM.
L1CAM/CD171 is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.
Specifications
Specifications
| Accession Number | antigen identified by monoclonal antibody R1; Caml1; CD 171; CD171; CD171 molecule; Hsas; HSAS1; Hyd; L1; L1 cell adhesion molecule; L1cam; MASA; MIC5; N-CAM L1; NCAML1; N-CAML1; N-CAM-L1; NCAM-L1; Nerve-growth factor-inducible large external glycoprotein; neural cell adhesion molecule L1; NILE; S10; sCD171; sL1 CAM; sL1CAM; soluble CD 171; soluble CD171; soluble L1 CAM; soluble L1CAM; SPG1 |
| Assay Range | 0.8 to 200 pg/mL |
| Assay Sensitivity | 0.8 pg/mL |
| Conjugate | HRP |
| Product Type | ELISA |
| Sample Type | Plasma, Serum, Supernatant |
| For Use With (Equipment) | Colorimetric Microplate Reader |
| Gene ID (Entrez) | 3897 |
| Gene Symbol | L1CAM |
| Interassay CV | <12% |
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