missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Recombinant Proteins
  4. Gibco™ Human IL-4 Recombinant Protein

Gibco™ Human IL-4 Recombinant Protein

Catalog No. p-5232757
Encompass
Change view
Click to view available options
Quantity:
10 μg
100 μg
25 μg
1 mg
4 product options available for selection
Product selection table with 4 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PHC0041 100 μg
PHC0043 1 mg
PHC0044 10 μg
PHC0045 25 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 4 options available.
4 options
Catalog No. PHC0041 Supplier Gibco™ Supplier No. PHC0041
Only null left

Description

Recombinant Protein

Carrier-Free Reconstitution: Centrifuge the vial briefly, before opening to bring the contents to the bottom. Reconstitute the lyophilized protein in sterile, deionized water to 0.1-1.0 mg/mL to regain full activity. Apportion the reconstituted protein into working aliquots and store at ≤-20°C. Make any further dilutions of the reconstituted protein in low endotoxin medium or buffered solution with FCS or tissue culture grade BSA. Storage Store the lyophilized protein at 2-8°C, preferably desiccated. Upon reconstitution, apportion into working aliquots and store at ≤-20°C (not in a frost-free freezer). Avoid repeated freeze-thaw cycles.

Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.

Specifications

Accession Number P05112
For Use With (Application) Bioactivity
Formulation Protein with no preservative
Gene ID (Entrez) 3565
Molecular Weight (g/mol) 14.9 kDa
Name Human IL-4
Purification Method Purified
Quantity 100 μg
Storage Requirements 4°C
Regulatory Status RUO
Endotoxin Concentration <0.1 ng/μg
Gene Alias B cell growth factor 1; B_cell stimulatory factor 1; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; cytokine; H-IL-4; IGG1 induction factor; IL2; IL4; Il-4; Il4e12; ILN; Interleukin; interleukin 4; interleukin 4 variant 2; interleukin 4 variant IL-4delta2; interleukin 4 variant IL-4delta3; interleukin 4 variant IL-4int2A; interleukin 4 variant IL-4int3A; interleukin 4 variant IL-4int3B; Interleukin4; interleukin-4; interleukin-4 precursor; lymphocyte stimulatory factor 1; MGC79402; M-IL-4; Pitrakinra
Common Name IL-4
Gene Symbol Il4
Biological Activity ED50 = 0.05 - 0.4 ng/mL; determined by the dose-dependent proliferation of human TF-1 cells.
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Sequence HKCDITLQEI IKTLNSLTEQ KTLCTELTVT DIFAASKNTT EKETFCRAAT VLRQFYSHHE KDTRCLGATA QQFHRHKQLI RFLKRLDRNL WGLAGLNSCP VKEANQSTLE NFLERLKTIM REKYSKCSS
Content And Storage 4°C
Classification Carrier-Free
Activity ED50 = 0.05 - 0.4 ng/mL; determined by the dose-dependent proliferation of human TF-1 cells.
Endotoxin Level <0.1 ng/μg
Shipping Condition Wet Ice
Expression System E. coli
Protein Family Cytokines & Receptors
Protein Form Recombinant, Ligand
Form Lyophilized
Protein Subtype Interleukins
Research Category Immunology, Stem Cell Research, Inflammation
Product Line Gibco
Purity or Quality Grade >95% by SDS-PAGE
Show More Show Less