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Gibco™ Human IL-24 Recombinant Protein, PeproTech®

Catalog No. 2003501m
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Quantity:
100 μg
2 x 500 μg
20 μg
250 μg
5 μg
50 μg
500 μg
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Catalog No. Quantity
2003501M 2 x 500 μg
20035100UG 100 μg
200351MG 2 x 500 μg
2003520UG 20 μg
20035250UG 250 μg
20035500UG 500 μg
2003550UG 50 μg
200355UG 5 μg
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Catalog No. 2003501M missing translation for 'mfr' Gibco™ missing translation for 'supplierNo' 2003501M

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Description

Recombinant Protein

200-35-1MG will be provided as 2 x 500 μg (200-35-500UG). Recombinant Human IL-24 is an 18.9 kDa glycoprotein that contains 161 amino acid residues, including a C-terminal His-tag. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.

Specifications

Accession Number Q13007
For Use With (Application) Functional Assay
Formulation protein with no preservative
Gene ID (Entrez) 11009
Molecular Weight (g/mol) 18.9 kDa
Name Human IL-24
Quantity 2 x 500 μg
Source CHO cells
Regulatory Status RUO
Endotoxin Concentration <1 EU/ μg
Gene Alias C49A; Cytokine-like protein Mob-5; FISP; IL 24; IL10B; Il24; IL-24; IL-4-induced secreted protein; Interleukin; interleukin 24; interleukin-24; Mda7; MDA-7; melanocyte-associated Mda-7; melanoma differentiation-associated gene 7 protein; Mob5; ST16; suppression of tumorigenicity 16 (melanoma differentiation); Suppression of tumorigenicity 16 protein; Th2-specific cytokine FISP
Common Name IL24
Gene Symbol IL24
Conjugate Unconjugated
Recombinant Recombinant
Protein Tag His-tag
Sequence QEFHFGPCQV KGVVPQKLWE AFWAVKDTMQ AQDNITSARL LQQEVLQNVS DAESCYLVHT LLEFYLKTVF KNYHNRTVEV RTLKSFSTLA NNFVLIVSQL QPSQENEMFS IRDSAHRRFL LFRRAFKQLD VEAALTKALG EVDILLTWMQ KFYKLHHHHH H
Content And Storage -20°C
Expression System CHO cells
Form Lyophilized
Purity or Quality Grade ≥ 95% by SDS-PAGE gel and HPLC analyses.
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