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  5. Invitrogen™ Human IL-23 R ELISA Kit

Invitrogen™ Human IL-23 R ELISA Kit

Catalog No. EH268RBX5
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5 x 96 Tests
96 Tests
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EH268RBX5 5 x 96 Tests
EH268RB 96 Tests
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Description

ELISA

Human IL-23 R quantitates human IL-23 R in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human IL-23 R.

IL-23R is a 629 aa, novel subunit of the receptor for cytokine IL23A/IL23 which pairs with the receptor molecule IL12RB1/IL12R beta 1and thus take part in IL23A signaling. Signal transduction analysis confirms that this protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. Alternative splicing results in six spliced isoforms of IL-23R. Reports suggest that IL-23R plays an important role in psoriasis pathogenesis and is also a potential therapeutic target in inflammatory bowel disease.

Specifications

Accession Number IBD17; IL 23 R; IL-23 receptor; Il23r; IL-23 R; interleukin 23 receptor; interleukin 23 receptor-like; interleukin-23 receptor
Assay Range 0.2 to 50 ng/mL
Assay Sensitivity 0.2 ng/mL
Conjugate HRP
Product Type ELISA
Sample Type Plasma, Serum, Supernatant
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 149233
Gene Symbol Il23r
Interassay CV <12%
Intraassay CV <10
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
Label or Dye HRP
Quantity 5 x 96 Tests
Regulatory Status RUO
Sample Volume Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
Storage Requirements 2°C to 8°C
Target IL23R
Test Time 1 hrs 20 mins
Total Assay Time 4 hrs 45 mins
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