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Gibco™ Human IL-18 Recombinant Protein 
Recombinant Protein
Supplier: Gibco™ PHC0186
Description
Reconstitution: We recommend the vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute with 250 μL ice cold, sterile, distilled water on ice. Storage: Store this lyophilized preparation at -20°C, preferably desiccated. Upon reconstitution, the protein may be stored at 2°C to 8°C for up to one week. For long term storage of the reconstituted protein, apportion into working aliquots and store at -80°C. Avoid repeated freeze/thaw cycles.
The protein encoded by this gene is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein can specifically interact with this cytokine, and thus negatively regulate its biological activity.Specifications
| Q14116 | |
| PBS with 0.1% BSA, 1% sucrose and no preservative | |
| 18 kDa | |
| Purified | |
| -20°C | |
| <0.1 ng/μg | |
| IL-18 | |
| Determined by the dose-dependent production of IFN-gamma by human KG-1 myelomonocyte cells. | |
| Unconjugated | |
| Recombinant | |
| -20°C | |
| Approved for shipment on Wet or Dry Ice | |
| Cytokines & Receptors | |
| Lyophilized | |
| Inflammation, Immunology | |
| >90% by SDS-PAGE |
| Bioactivity | |
| 3606 | |
| Human IL-18 | |
| 25 μg | |
| RUO | |
| cytokine; iboctadekin; IFN-gamma-inducing factor; IGIF; il 18; IL-1 gamma; IL18; IL-18; IL1F4; IL-1g; ILN; interferon gamma inducing factor; interferon gamma-inducing factor; interferon-gamma-inducing factor; Interleukin; interleukin 18; interleukin 18 (interferon-gamma-inducing factor); interleukin-1 gamma; Interleukin18; Interleukin-18; interleukin-18 proprotein; interleukin-18-like protein; MGC12320 | |
| IL18 | |
| Protein | |
| Human | |
| Human IL-18, amino acids 37-193 | |
| Determined by the dose-dependent production of IFN-gamma by human KG-1 myelomonocyte cells. | |
| E. coli | |
| Recombinant, Ligand | |
| Interleukins | |
| Gibco |