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Gibco™ Human IGF-BP2 Recombinant Protein, PeproTech®

Catalog No. 35006B5UG
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Quantity:
100 μg
2 x 500 μg
20 μg
250 μg
5 μg
50 μg
500 μg
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Catalog No. Quantity
35006B5UG 5 μg
35006B01M 2 x 500 μg
35006B100UG 100 μg
35006B20UG 20 μg
35006B250UG 250 μg
35006B500UG 500 μg
35006B50UG 50 μg
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Catalog No. 35006B5UG Supplier Gibco™ Supplier No. 35006B5UG

Description

Recombinant Protein

350-06B-1MG will be provided as 2 x 500 μg (350-06B-500UG). Recombinant Human IGF-BP2 is a 31.5 kDa protein consisting of 289 amino acid residues including the IGF-BP domain and thyroglobulin type-I domain. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis.

IGFBP2 (insulin-like growth factor binding protein 2) is a member of the ISGBP family which bind various IGFs. IGFBP2 is overexpressed in a wide spectrum of cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The overexpression of IGFBP2 also correlates with the aggressiveness of some tumors. IGFBP2 activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness.

Specifications

Accession Number P18065
For Use With (Application) Control, Bioactivity
Formulation Protein with no preservative
Gene ID (Entrez) 3485
Molecular Weight (g/mol) 31.5 kDa
Name Human IGF-BP2
Purification Method Purified
Quantity 5 μg
Source Insect cells
Storage Requirements -20°C
Regulatory Status RUO
Endotoxin Concentration <1 EU/μg
Gene Alias AI255832; BP2; BRL-BP; IBP2; IBP-2; IGF binding protein 2; IGF-binding protein 2; IGFBP; IGFBP2; IGFBP-2; IGF-BP53; ILGFBPA; Insulin like growth factor binding protein; insulin like growth factor binding protein 2; insulin-like growth factor binding protein 2; insulin-like growth factor binding protein 2, 36kDa; insulin-like growth factor-binding protein 2; mIGFBP-2; OTTHUMP00000207753
Common Name IGFBP2
Gene Symbol IGFBP2
Biological Activity Determined by its ability to inhibit IGF-I induced proliferation of FDC-P1 cells.
Product Type Protein
Conjugate Unconjugated
Recombinant Recombinant
Sequence EVLFRCPPCT PERLAACGPP PVAPPAAVAA VAGGARMPCA ELVREPGCGC CSVCARLEGE ACQVYTPRCG QGLRCYPHPG SELPLQALVM GEGTCEKRRD AEYGASPEQV ADNGDDHSEG GLVENHVDST MNMLGGGGSA GRKPLKSGMK ELAVFREKVT EQHRQMGKGG KHHLGLEEPK KLRPPPARTP CQQELDQVLE RISTMRLPDE RGPLEHLYSL HIPNCDKHGL YNLKQCKMSL NGQRGECWCV NPNTGKLIQG APTIRGDPEC HLFYNEQQEA RGVHTQRMQ
Content And Storage -20°C
Activity Determined by its ability to inhibit IGF-I induced proliferation of FDC-P1 cells.
Expression System Insect cells
Form Lyophilized
Purity or Quality Grade ≥ 98% by SDS-PAGE gel and HPLC analyses.
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