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Invitrogen™ Human HYPK (aa 54-120) Control Fragment Recombinant Protein

Catalog No. RP101704
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100 μL
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Catalog No. Quantity
RP101704 100 μL
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Catalog No. RP101704 Supplier Invitrogen™ Supplier No. RP101704

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63098. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Huntingtin-interacting protein K (HYPK) has a chaperone-like activity preventing polyglutamine (polyQ) aggregation of HTT. It protects against HTT polyQ-mediated apoptosis in Neuro2a neuronal cells. HYPK is required for optimal NAA10-NAA15 complex-mediated N-terminal acetylation.

Specifications

Accession Number Q9NX55
Concentration ≥5.0 mg/mL
For Use With (Application) Neutralization, Control
Formulation PBS, 1M urea with no preservative; pH 7.4
Gene ID (Entrez) 25764
Name Human HYPK (aa 54-120) Control Fragment
pH Range 7.4
Purification Method Purified
Quantity 100 μL
Storage Requirements -20°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias C15orf63; FLJ20431; HSPC136; huntingtin interacting protein K; huntingtin yeast partner K; Huntingtin-interacting protein K; HYPK
Common Name HYPK
Gene Symbol HYPK
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence TAMSVIGDRRSREQKAKQEREKELAKVTIKKEDLELIMTEMEISRAAAERSLREHMGNVVEALIALT
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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