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Invitrogen™ Human HOXB8 (aa 205-239) Control Fragment Recombinant Protein

Catalog No. RP108062
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100 μL
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Catalog No. Quantity
RP108062 100 μL
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Catalog No. RP108062 Supplier Invitrogen™ Supplier No. RP108062
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Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (89%), Rat (89%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-67398 (PA5-67398. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.

Specifications

Accession Number P17481
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 3218
Name Human HOXB8 (aa 205-239) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias homeo box 2 D; homeo box B8; homeobox B8; homeobox gene B8; homeobox protein Hox-2.4; Homeobox protein Hox-2 D; homeobox protein Hox-B8; homeobox protein R1a; HO x 2; Hox-2.4; Ho x 2.4 homeobox homolog; HO x 2 D; Ho x 2r1a; Hoxb8; Hoxb-8
Common Name HOXB8
Gene Symbol HOXB8
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence NNKDKFPSSKCEQEELEKQKLERAPEAADEGDAQK
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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