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Invitrogen™ Human GSR (aa 251-327) Control Fragment Recombinant Protein

Recombinant Protein

Supplier:  Invitrogen™ RP109073

Catalog No. RP109073


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Description

Description

Highest antigen sequence indentity to the following orthologs: Mouse (84%), Rat (84%). This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
Specifications

Specifications

P00390
Blocking Assay, Control
2936
100 μL
AI325518; D8Ertd238e; epididymis luminal protein 75; epididymis secretory sperm binding protein Li 122 m; GLUR; glutathione reductase; glutathione reductase 1; glutathione reductase, mitochondrial; glutathione S-reductase; glutathione-disulfide reductase; GR; Gr1; Gr-1; GRase; GRD1; GSR; HEL-75; HEL-S-122 m; hypothetical protein LOC553575; zgc:110010
Gsr
Human
His-ABP-tag
-20°C, Avoid Freeze/Thaw Cycles
Liquid
≥5.0 mg/mL
1 M urea, PBS with no preservative; pH 7.4
Human GSR (aa 251-327) Control Fragment
RUO
GSR
Unconjugated
Recombinant
SALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEVKKTLSGLEVSMVTAVPGRLPVMTMIPDVD
E. coli
>80% by SDS-PAGE and Coomassie blue staining
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