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Gibco™ Human Growth Hormone Recombinant Protein, PeproTech® DFS Item

Recombinant Protein

$125.66 - $1241.41

Specifications

Accession Number P01241
For Use With (Application) Functional Assay
Formulation protein with no preservative
Gene ID (Entrez) 2688
Molecular Weight (g/mol) 22.3 kDa
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Products 6
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
10040100UG DFS Item
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Gibco™
10040100UG
100 μg
Each for $335.10
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1004010UG DFS Item
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Gibco™
1004010UG
10 μg
Each for $125.66
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100401MG DFS Item
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Gibco™
100401MG
1 mg
Each for $1,241.41
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10040250UG DFS Item
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Gibco™
10040250UG
250 μg
Each for $435.06
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10040500UG DFS Item
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Gibco™
10040500UG
500 μg
Each for $746.37
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1004050UG DFS Item
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Gibco™
1004050UG
50 μg
Each for $302.74
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Description

Description

Recombinant Human Growth Hormone is a 22.3 kDa, single, non-glycosylated polypeptide chain containing 192 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The GH1 gene, along with 4 additional related genes, is located at the growth hormone locus on chromosome 17. The five genes share a remarkably high degree of sequence identity. Alternative splicing results in 5 isoforms ranging from approximately 19 kDa to 24 kDa. HGH is produced by the somatotroph cells in the pituitary. It acts through binding to membrane receptors that belong to the cytokine receptor subfamily. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. Mutations or deletions in the gene lead to growth hormone deficiency and short stature.
Specifications

Specifications

P01241
protein with no preservative
22.3 kDa
E. coli
<1 EU/ μg
Growth Hormone
Determined by its ability to stimulate the proliferation of rat Nb2-11 cells. The expected ED50 is = 0.05 ng/ml, corresponding to a specific activity of = 2 x 10^7 units/mg
Recombinant
-20°C
Lyophilized
Functional Assay
2688
Human Growth Hormone
RUO
dog growth hormone; GH; Gh1; GHB1; GHB5; GHN; GH-N; Growth hormone; growth hormone 1; growth hormone 12; growth hormone B1; growth hormone B5; growth hormone precursor; HGH; hGH-N; IGHD1B; pituitary growth hormone; RNGHGP; Somatotropin
Gh1
Unconjugated
MFPTIPLSRL FDNAMLRAHR LHQLAFDTYQ EFEEAYIPKE QKYSFLQNPQ TSLCFSESIP TPSNREETQQ KSNLELLRIS LLLIQSWLEP VQFLRSVFAN SLVYGASDSN VYDLLKDLEE GIQTLMGRLE DGSPRTGQIF KQTYSKFDTN SHNDDALLKN YGLLYCFRKD MDKVETFLRI VQCRSVEGSC GF
E. coli
≥ 98% by SDS-PAGE gel and HPLC analyses.
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