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Invitrogen™ Human Granzyme H ELISA Kit

Catalog No. EH231RBX5
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5 x 96 Tests
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EH231RBX5 5 x 96 Tests
EH231RB 96 Tests
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ELISA

Human Granzyme H quantitates human Granzyme H in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Granzyme H.

This gene encodes a member of the peptidase S1 family of serine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a chymotrypsin-like protease. This protein is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. This gene is present in a gene cluster with another member of the granzyme subfamily on chromosome 14.

Specifications

Accession Number Cathepsin G-like 2; cathepsin G-like 2, protein h-CCPX; CCP-X; CGL2; CGL-2; CSP-C; CTLA1; CTSGL2; Cytotoxic serine protease C; Cytotoxic T-lymphocyte proteinase; cytotoxic T-lymphocyte-associated serine esterase 1; cytotoxin serine protease-C; granzyme H; granzyme H (cathepsin G-like 2, protein h-CCPX); GZMH
Assay Range 12.5 to 3,000 pg/mL
Assay Sensitivity 12.5 pg/mL
Conjugate HRP
Product Type ELISA
Sample Type Plasma, Serum, Supernatant
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 2999
Gene Symbol GZMH
Interassay CV <12%
Intraassay CV <10
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
Label or Dye HRP
Quantity 5 x 96 Tests
Regulatory Status RUO
Sample Volume Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
Storage Requirements 2°C to 8°C
Target Granzyme H
Test Time 1 hrs 20 mins
Total Assay Time 4 hrs 45 mins
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