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Gibco™ Human FGF-10, Animal-Free Recombinant Protein, PeproTech®

Catalog No. 503077069
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250 μg
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Catalog No. Quantity
503077069 250 μg
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Catalog No. 503077069 Supplier Gibco™ Supplier No. AF10026250UG

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Recombinant Protein

Recombinant Human FGF-10 is a 19.3 kDa protein consisting of 170 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

FGF10 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This protein is also implicated to be a primary factor in the process of wound healing.

Specifications

Accession Number O15520
For Use With (Application) Control, Bioactivity
Format Lyophilized
Formulation Protein with no preservative
Gene ID (Entrez) 2255
Molecular Weight (g/mol) 19.3 kDa
Name Human FGF-10, Animal-Free
Purification Method Purified
Quantity 250 μg
Storage Requirements -20°C
Regulatory Status RUO
Endotoxin Concentration <0.1 EU/μg
Gene Alias AEY17; BB213776; FGF; Fgf10; FGF-10; Fibroblast growth factor; Fibroblast growth factor 10; Gsfaey17; Keratinocyte growth factor 2; produced by fibroblasts of urinary bladder lamina propria
Common Name FGF10
Gene Symbol FGF10
Biological Activity Determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors. The expected ED50 is ≤ 0.5 ng/ml corresponding to a specific activity of ≥ 2 x 10^6 units/mg
Product Type Protein
Conjugate Unconjugated
Recombinant Recombinant
Sequence MLGQDMVSPE ATNSSSSSFS SPSSAGRHVR SYNHLQGDVR WRKLFSFTKY FLKIEKNGKV SGTKKENCPY SILEITSVEI GVVAVKAINS NYYLAMNKKG KLYGSKEFNN DCKLKERIEE NGYNTYASFN WQHNGRQMYV ALNGKGAPRR GQKTRRKNTS AHFLPMVVHS
Content And Storage -20°C
Activity Determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors. The expected ED50 is ≤ 0.5 ng/ml corresponding to a specific activity of ≥ 2 x 10^6 units/mg.
Expression System E. coli
Form Lyophilized
Purity or Quality Grade ≥ 95% by SDS-PAGE gel and HPLC analyses.
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