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Gibco™ Human FGF-10, Animal-Free Recombinant Protein, PeproTech®

Numéro de catalogue. 503077069
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Quantité:
250 μg
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Numéro de catalogue. Quantité
503077069 250 μg
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Numéro de catalogue. 503077069 Fournisseur Gibco™ Code fournisseur AF10026250UG

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Recombinant Protein

Recombinant Human FGF-10 is a 19.3 kDa protein consisting of 170 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

FGF10 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This protein is also implicated to be a primary factor in the process of wound healing.

Spécifications

Numéro d'enregistrement O15520
À utiliser avec (application) Control, Bioactivity
Format Lyophilized
Formule Protein with no preservative
ID du gène (Entrez) 2255
Poids moléculaire (g/mol) 19.3 kDa
Nom Human FGF-10, Animal-Free
Méthode de purification Purified
Quantité 250 μg
Conditions de stockage -20°C
Statut réglementaire RUO
Concentration en endotoxines <0.1 EU/μg
Alias du gène AEY17; BB213776; FGF; Fgf10; FGF-10; Fibroblast growth factor; Fibroblast growth factor 10; Gsfaey17; Keratinocyte growth factor 2; produced by fibroblasts of urinary bladder lamina propria
Nom usuel FGF10
Symbole de gène FGF10
Activité biologique Determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors. The expected ED50 is ≤ 0.5 ng/ml corresponding to a specific activity of ≥ 2 x 10^6 units/mg
Type de produit Protein
Conjugué Unconjugated
Recombinant Recombinant
Séquence MLGQDMVSPE ATNSSSSSFS SPSSAGRHVR SYNHLQGDVR WRKLFSFTKY FLKIEKNGKV SGTKKENCPY SILEITSVEI GVVAVKAINS NYYLAMNKKG KLYGSKEFNN DCKLKERIEE NGYNTYASFN WQHNGRQMYV ALNGKGAPRR GQKTRRKNTS AHFLPMVVHS
Contenu et stockage -20°C
Activité Determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors. The expected ED50 is ≤ 0.5 ng/ml corresponding to a specific activity of ≥ 2 x 10^6 units/mg.
Système d’expression E. coli
Forme Lyophilized
Grade de qualité ou de pureté ≥ 95% by SDS-PAGE gel and HPLC analyses.
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