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Gibco™ Human CNTF, Animal-Free Recombinant Protein, PeproTech® 
Recombinant Protein
$363.00 - $5000.00
Specifications
| Accession Number | P26441 |
|---|---|
| For Use With (Application) | Functional Assay |
| Formulation | protein with no preservative |
| Gene ID (Entrez) | 1270 |
| Molecular Weight (g/mol) | 22.8 kDa |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AF45013100
|
Gibco™
AF45013100UG |
100 μg |
Each for $1,034.00
|
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AF450131MG
|
Gibco™
AF450131MG |
1 mg |
Each for $5,000.00
|
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|
AF4501320UG
|
Gibco™
LSAF4501320UG |
20 μg |
Each for $363.00
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|
AF45013500
|
Gibco™
AF45013500UG |
500 μg |
Each for $2,990.00
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Description
Recombinant Human CNTF is synthesized as a 199 amino acid polypeptide (22.8 kDa) lacking a hydrophobic N-terminal signal for secretion. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of ZFP91 and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.Specifications
| P26441 | |
| protein with no preservative | |
| 22.8 kDa | |
| E. coli | |
| <0.1 EU/ μg | |
| CNTF | |
| Determined by its ability to stimulate proliferation of human TF-1 cells using an ED50 concentration range of 50-150 ng/ml | |
| Recombinant | |
| -20°C | |
| Lyophilized |
| Functional Assay | |
| 1270 | |
| Human CNTF, Animal-Free | |
| RUO | |
| AI429687; Ciliary neurotrophic factor; ciliary neurotropic factor; Cntf; HCNTF; H-CNTF | |
| CNTF | |
| Unconjugated | |
| AFTEHSPLTP HRRDLCSRSI WLARKIRSDL TALTQSYVKH QGLNKNINLD SADGMPVAST DQWSQLTQAQ RLQQNLQAYR TFHVLLARLL QDQQVHFTPT QGDFHQAIHT LLLQVAAFAY QIQQLMILLQ YKIPRNQADG MPINVGDGGL FQKKLWGLKV LQQLSQWTVR SIHDLRFISS HQTGIPARGS HYIANNKKM | |
| E. coli | |
| ≥ 98% by SDS-PAGE gel and HPLC analyses. |