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Invitrogen™ Human CIC (aa 1410-1521) Control Fragment Recombinant Protein

Recombinant Protein

Supplier:  Invitrogen™ RP102474

Catalog No. RP102474

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Description

Description

Highest antigen sequence indentity to the following orthologs: Mouse (98%), Rat (98%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-83721 (PA5-83721. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46.
Specifications

Specifications

Q96RK0
Blocking Assay, Control
23152
100 μL
1200010B10Rik; Capicua; capicua homolog; capicua homolog (Drosophila); capicua transcriptional repressor; CIC; KIAA0306; mKIAA0306; Protein capicua homolog; protein capicua homolog; LOW QUALITY PROTEIN: protein capicua homolog
CIC
Human
His-ABP-tag
-20°C, Avoid Freeze/Thaw Cycles
Liquid
≥5.0 mg/mL
1 M urea, PBS with no preservative; pH 7.4
Human CIC (aa 1410-1521) Control Fragment
RUO
CIC
Unconjugated
Recombinant
PKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQA
E. coli
>80% by SDS-PAGE and Coomassie blue staining
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