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Gibco™ Human CCL20 (MIP-3 alpha) Recombinant Protein
Recombinant Protein
Supplier: Gibco™ PHC1234
Description
Carrier-Free Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute recombinant human MIP-3 alpha in sterile, distilled water to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in tissue culture grade buffered solutions with heat inactivated fetal calf serum or low endotoxin BSA. Storage: This lyophilized preparation is stable at 2°C to 8°C, but should be kept at -20°C for long term storage, preferably desiccated. Apportion the reconstituted preparation into working aliquots and store at -20°C. Avoid repeated freeze/thaw cycles.
Macrophage Inflammatory Protein-3 alpha (MIP-3alpha), also called CCL20, is expressed in the liver, lungs, lymph nodes and peripheral blood lymphocytes. MIP-3alpha is strongly up regulated by inflammatory signals, and down regulated by the anti-inflammatory cytokine IL-10. MIP3alpha signals through the G protein-coupled receptor, CCR6, and acts as a chemoattractant to lymphocytes and dendritic cells.Specifications
| P78556 | |
| Protein with no preservative | |
| 8 kDa | |
| Purified | |
| -20°C | |
| <0.1 ng/μg | |
| CCL20 | |
| ED50 = 10 - 50 ng/mL; determined by the dose-dependent chemotaxis of human T-cells. | |
| Unconjugated | |
| Recombinant | |
| -20°C | |
| ED50 = 10 - 50 ng/mL; determined by the dose-dependent chemotaxis of human T-cells. | |
| Wet Ice | |
| Chemokines & Receptors | |
| Lyophilized | |
| Immunology, Inflammation, Signal Transduction, Neurobiology | |
| >98% by SDS-PAGE |
| Bioactivity | |
| 6364 | |
| Human CCL20 (MIP-3 alpha) | |
| 20 μg | |
| RUO | |
| beta chemokine exodus-1; beta-chemokine exodus-1; CC chemokine LARC; CC chemokine ST38; C-C motif chemokine 20; C-C motif chemokine ligand 20; Ccl20; CCL20(1-64); CCL20(1-67); CCL20(2-70); chemokine (C-C motif) ligand 20; CKb4; Exodus; exodus-1; LARC; Liver and activation-regulated chemokine; macrophage inflammatory protein 3 alpha; MIP 3 a; MIP 3 α; MIP 3alpha; MIP 3α; MIP3 a; MIP3 alpha; MIP3 α; MIP-3[a]; MIP3A; MIP-3A; MIP-3-alpha; M-MIP-3-alpha; SCYA20; small inducible cytokine subfamily A (Cys-Cys), member 20; small inducible cytokine subfamily A20; small-inducible cytokine A20; St38 | |
| CCL20 | |
| Protein | |
| Human | |
| Human CCL20 recombinant protein contains 70 amino acids | |
| Carrier-Free | |
| <0.1 ng/μg | |
| E. coli | |
| Recombinant, Ligand | |
| MIP (Macrophage Inflammatory Protein) Chemokines | |
| Gibco |