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Gibco™ Human CCL20 (MIP-3 alpha) Recombinant Protein DFS Item

Recombinant Protein

Supplier:  Gibco™ PHC1234

Catalog No. PHC1234


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Description

Description

Carrier-Free Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute recombinant human MIP-3 alpha in sterile, distilled water to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in tissue culture grade buffered solutions with heat inactivated fetal calf serum or low endotoxin BSA. Storage: This lyophilized preparation is stable at 2°C to 8°C, but should be kept at -20°C for long term storage, preferably desiccated. Apportion the reconstituted preparation into working aliquots and store at -20°C. Avoid repeated freeze/thaw cycles.

Macrophage Inflammatory Protein-3 alpha (MIP-3alpha), also called CCL20, is expressed in the liver, lungs, lymph nodes and peripheral blood lymphocytes. MIP-3alpha is strongly up regulated by inflammatory signals, and down regulated by the anti-inflammatory cytokine IL-10. MIP3alpha signals through the G protein-coupled receptor, CCR6, and acts as a chemoattractant to lymphocytes and dendritic cells.
Specifications

Specifications

P78556
Protein with no preservative
8 kDa
Purified
-20°C
<0.1 ng/μg
CCL20
ED50 = 10 - 50 ng/mL; determined by the dose-dependent chemotaxis of human T-cells.
Unconjugated
Recombinant
-20°C
ED50 = 10 - 50 ng/mL; determined by the dose-dependent chemotaxis of human T-cells.
Wet Ice
Chemokines & Receptors
Lyophilized
Immunology, Inflammation, Signal Transduction, Neurobiology
>98% by SDS-PAGE
Bioactivity
6364
Human CCL20 (MIP-3 alpha)
20 μg
RUO
beta chemokine exodus-1; beta-chemokine exodus-1; CC chemokine LARC; CC chemokine ST38; C-C motif chemokine 20; C-C motif chemokine ligand 20; Ccl20; CCL20(1-64); CCL20(1-67); CCL20(2-70); chemokine (C-C motif) ligand 20; CKb4; Exodus; exodus-1; LARC; Liver and activation-regulated chemokine; macrophage inflammatory protein 3 alpha; MIP 3 a; MIP 3 α; MIP 3alpha; MIP 3α; MIP3 a; MIP3 alpha; MIP3 α; MIP-3[a]; MIP3A; MIP-3A; MIP-3-alpha; M-MIP-3-alpha; SCYA20; small inducible cytokine subfamily A (Cys-Cys), member 20; small inducible cytokine subfamily A20; small-inducible cytokine A20; St38
CCL20
Protein
Human
Human CCL20 recombinant protein contains 70 amino acids
Carrier-Free
<0.1 ng/μg
E. coli
Recombinant, Ligand
MIP (Macrophage Inflammatory Protein) Chemokines
Gibco
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