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Gibco™ Human CCL13 (MCP-4) Recombinant Protein 
Recombinant Protein
Supplier: Gibco™ PHC1154
Description
Carrier-Free Reconstitution: We recommend that the vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute this protein in sterile, distilled water to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in tissue culture grade buffered solutions with heat inactivated fetal calf serum or low endotoxin BSA. Storage: Store lyophilized at ≤+4°C, preferably desiccated. Store reconstituted MCP-4 at -20°C in working aliquots. Avoid repeated freeze-thaw cycles.
Monocyte Chemotactic Protein 4 (MCP-4), also called CCL13, is induced by inflammatory proteins such as IL-1 and TNFalpha. MCP-4 is a ligand for three different G protein coupled receptors, CCR2, CCR3 and CCR5. MCP-4 activates signaling in monocytes, T lymphocytes, eosinophils and basophils and this signaling is associated with the allergic response.Specifications
| Q99616 | |
| Protein with no preservative | |
| 8.6 kDa | |
| Purified | |
| 4°C | |
| <0.1 ng/μg | |
| MCP-4 | |
| ED50 = 10-100 ng/mL; determined by the dose-dependent chemotaxis of human blood cells. | |
| Unconjugated | |
| Recombinant | |
| 4°C | |
| ED50 = 10-100 ng/mL; determined by the dose-dependent chemotaxis of human blood cells. | |
| Approved for shipment on Wet or Dry Ice | |
| Chemokines & Receptors | |
| Lyophilized | |
| Signal Transduction, Immunology | |
| >98% by SDS-PAGE |
| Bioactivity | |
| 6357 | |
| Human CCL13 (MCP-4) | |
| 20 μg | |
| RUO | |
| C-C motif chemokine 13; C-C motif chemokine 13, long chain; C-C motif chemokine 13, medium chain; C-C motif chemokine 13, short chain; C-C motif chemokine ligand 13; CCL 13; CCL13; chemokine (C-C motif) ligand 13; CKb10; CK-beta-10; H-MCP-4; MCP4; MCP-4; Monocyte chemoattractant protein 4; monocyte chemotactic protein 4; NCC1; NCC-1; new CC chemokine 1; SCYA13; SCYL1; small inducible cytokine subfamily A (Cys-Cys), member 13; small-inducible cytokine A13 | |
| CCL13 | |
| Protein | |
| Human | |
| Human CCL13 recombinant protein contains 75 amino acids | |
| Carrier-Free | |
| <0.1 ng/μg | |
| E. coli | |
| Recombinant, Ligand | |
| MCPâMCAF Chemokines | |
| Gibco |