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Invitrogen™ Human Carboxypeptidase B2 Native Protein

Catalog No. PIRP43139
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50 μg
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PIRP43139 50 μg
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Catalog No. PIRP43139 Supplier Invitrogen™ Supplier No. RP43139
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Description

Native Protein

RP-43139 contains native human Thrombin Activatable Fibrinolysis Inhibitor protein. RP-43139 may be used as a positive control in many immunological assays. The product is of human blood/plasma origin. Although the starting material was tested prior to initiation of the manufacturing process, and was found negative or nonreactive for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II, extreme caution should be used when handling this material as there is a margin of error in all tests. This product is to be used for IN VITRO research purposes only, and is not intended for clinical or diagnostic use!

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for its gene and its promoter region.

Specifications

Accession Number Q96IY4
Concentration 2.3 mg/mL
For Use With (Application) Control
Formulation 0.02 M HEPES with 0.15 M NaCl and no preservative; pH 7.4
Gene ID (Entrez) 1361
Molecular Weight (g/mol) 60 kDa
Name Human Carboxypeptidase B2
pH Range 7.4
Quantity 50 μg
Source Human
Regulatory Status RUO
Gene Alias 1110032P04Rik; 4930405E17Rik; AI255929; carboxypeptidase B2; carboxypeptidase B2 (plasma); carboxypeptidase B2 (plasma, carboxypeptidase U); carboxypeptidase B-like protein; carboxypeptidase R; Carboxypeptidase U; Cpb2; CPR; CPU; pCPB; Plasma carboxypeptidase B; Tafi; thrombin-activable fibrinolysis inhibitor; thrombin-activatable fibrinolysis inhibitor
Common Name Carboxypeptidase B2
Gene Symbol CPB2
Conjugate Unconjugated
Species Human
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Form Liquid
Protein Subtype Native
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