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Invitrogen™ Human BRWD2 (aa 268-348) Control Fragment Recombinant Protein

Catalog No. RP97074
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100 μL
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RP97074 100 μL
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Catalog No. RP97074 Supplier Invitrogen™ Supplier No. RP97074

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (94%), Rat (94%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-58620 (PA5-58620. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

WDR11 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.

Specifications

Accession Number Q9BZH6
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 55717
Name Human BRWD2 (aa 268-348) Control Fragment
Quantity 100 μL
Gene Alias 2900055P10Rik; AW489876; bromodomain and WD repeat domain containing 2; bromodomain and WD repeat-containing protein 2; BRWD2; DR11; HH14; Kiaa1351; mKIAA1351; sensitization to ricin complex subunit 1; SRI1; WD repeat domain 11; WD repeat domain 15; WD repeat-containing protein 11; WD repeat-containing protein 15; WDR11; WDR15
Common Name BRWD2
Gene Symbol WDR11
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence ILILDLEVNQTVGVIAIERTGVPFLQVIPCFQRDGLFCLHENGCITLRVRRSYNNIFTTSNEEPDPDPVQELTYDLRSQCD
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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