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Gibco™ Human BMP-4 Recombinant Protein, PeproTech®

Numéro de catalogue. 12005ET10UG
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Quantité:
10 μg
100 μg
2 μg
2 x 500 μg
250 μg
50 μg
500 μg
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Numéro de catalogue. Quantité
12005ET10UG 10 μg
12005ET01M 2 x 500 μg
12005ET100 100 μg
12005ET250 250 μg
12005ET2UG 2 μg
12005ET500 500 μg
12005ET50UG 50 μg
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Numéro de catalogue. 12005ET10UG Fournisseur Gibco™ Code fournisseur LS12005ET10UG

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Recombinant Protein

120-05ET-1MG will be provided as 2 x 500 μg (120-05ET-500UG). PeproTech's E.coli-derived BMP-4 is a fully active homodimeric protein consisting of two 106 amino acid subunits, which correspond to amino acids 303-408 of the full length BMP-4 precursor. The calculated molecular weight of Recombinant Human BMP-4 (E.coli-derived) is 23.9 kDa. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis.

The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.

Spécifications

Numéro d'enregistrement P12644
À utiliser avec (application) Bioactivity, Control, Western Blot Control
Formule Protein with no preservative
ID du gène (Entrez) 652
Poids moléculaire (g/mol) 23.9 kDa
Nom Human BMP-4
Méthode de purification Purified
Quantité 10 μg
Sources E. coli
Conditions de stockage -20°C
Statut réglementaire RUO
Concentration en endotoxines <1 EU/μg
Alias du gène BMP; BMP2B; BMP-2B; Bmp2b1; Bmp2b-1; Bmp4; Bmp-4; BOMPR4A; Bone morphogenetic protein; Bone morphogenetic protein 2B; bone morphogenetic protein 4; bone morphogenetic protein 4 preproprotein; DVR4; Dvr-4; MCOPS6; OFC11; ZYME
Nom usuel BMP4
Symbole de gène BMP4
Activité biologique Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 5-10 ng/ml
Type de produit Protein
Conjugué Unconjugated
Recombinant Recombinant
Séquence KKNKNCRRHS LYVDFSDVGW NDWIVAPPGY QAFYCHGDCP FPLADHLNST NHAIVQTLVN SVNSSIPKAC CVPTELSAIS MLYLDEYDKV VLKNYQEMVV EGCGCR
Contenu et stockage -20°C
Activité Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 5-10 ng/ml.
Système d’expression E. coli
Forme Lyophilized
Grade de qualité ou de pureté ≥ 98% by SDS-PAGE gel and HPLC analyses.
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