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Gibco™ Human BAFF (BLyS), Animal-Free Recombinant Protein, PeproTech®

Catalog No. AF31013250U
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250 μg
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AF31013250U 250 μg
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Catalog No. AF31013250U Supplier Gibco™ Supplier No. AF31013250UG

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Description

Recombinant Protein

Recombinant Human soluble BAFF is a 152 amino acid polypeptide (17.0 kDa), which contains the TNF-like portion of the extracellular domain of BAFF. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

BAFF is a membrane bound cytokine expressed by B cell lineage cells. The soluble form of the cytokine binds to the receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. BAFF is a potent B cell activator, and important for the proliferation and differentiation of B cells. BAFF is also expressed by T lymphocytes and has been shown to promote T cell activation and survival. Isoforms representing alternatively spliced, and glycosylated variants have been identified.

Specifications

Accession Number Q9Y275
For Use With (Application) Functional Assay
Format Lyophilized
Formulation protein with no preservative
Gene ID (Entrez) 10673
Molecular Weight (g/mol) 17 kDa
Name Human BAFF (BLyS), Animal-Free
Purification Method HPLC, SDS-PAGE
Quantity 250 μg
Endotoxin Concentration <0.1 EU/ μg
Gene Alias ApoL related ligand TALL-1; b cell-activating factor; B lymphocyte stimulator; BAFF; B-cell-activating factor; B-lymphocyte stimulator; BLYS; CD257; D8Ertd387e; delta BAFF; Delta4 BAFF; dendritic cell-derived TNF-like molecule; DTL; RGD1561519; TALL1; TALL-1; THANK; TNF- and APOL-related leukocyte expressed ligand 1; TNF and ApoL-related leukocyte expressed ligand 1; TNF homolog that activates apoptosis; Tnfsf13b; TNFSF20; TNLG7A; tumor necrosis factor (ligand) superfamily member 13 b; tumor necrosis factor (ligand) superfamily, member 13 b; tumor necrosis factor (ligand) superfamily, member 20; tumor necrosis factor ligand 7 A; tumor necrosis factor ligand superfamily member 13 B; Tumor necrosis factor ligand superfamily member 13 b, membrane form; Tumor necrosis factor ligand superfamily member 13 b, soluble form; tumor necrosis factor superfamily member 13 b; tumor necrosis factor-like protein ZTNF4; UNQ401/PRO738; ZTNF4
Common Name BAFF (BLyS)
Gene Symbol TNFSF13B
Biological Activity Determined by a mouse splenocyte survival assay. The expected ED50 for this effect is 0.5-2.0 ug/ml
Product Type Protein
Conjugate Unconjugated
Recombinant Recombinant
Sequence AVQGPEETVT QDCLQLIADS ETPTIQKGSY TFVPWLLSFK RGSALEEKEN KILVKETGYF FIYGQVLYTD KTYAMGHLIQ RKKVHVFGDE LSLVTLFRCI QNMPETLPNN SCYSAGIAKL EEGDELQLAI PRENAQISLD GDVTFFGALK LL
Content And Storage -20°C
Activity Determined by a mouse splenocyte survival assay. The expected ED50 for this effect is 0.5-2.0 ug/ml
Expression System E. coli
Form Lyophilized
Purity or Quality Grade ≥ 95% by SDS-PAGE gel and HPLC analyses.
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