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Gibco™ Human BAFF (BLyS), Animal-Free Recombinant Protein, PeproTech®

Numéro de catalogue. AF31013250U
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Quantité:
250 μg
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Numéro de catalogue. Quantité
AF31013250U 250 μg
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Numéro de catalogue. AF31013250U Fournisseur Gibco™ Code fournisseur AF31013250UG

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Description

Recombinant Protein

Recombinant Human soluble BAFF is a 152 amino acid polypeptide (17.0 kDa), which contains the TNF-like portion of the extracellular domain of BAFF. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

BAFF is a membrane bound cytokine expressed by B cell lineage cells. The soluble form of the cytokine binds to the receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. BAFF is a potent B cell activator, and important for the proliferation and differentiation of B cells. BAFF is also expressed by T lymphocytes and has been shown to promote T cell activation and survival. Isoforms representing alternatively spliced, and glycosylated variants have been identified.

Spécifications

Numéro d'enregistrement Q9Y275
À utiliser avec (application) Functional Assay
Format Lyophilized
Formule protein with no preservative
ID du gène (Entrez) 10673
Poids moléculaire (g/mol) 17 kDa
Nom Human BAFF (BLyS), Animal-Free
Méthode de purification HPLC, SDS-PAGE
Quantité 250 μg
Concentration en endotoxines <0.1 EU/ μg
Alias du gène ApoL related ligand TALL-1; b cell-activating factor; B lymphocyte stimulator; BAFF; B-cell-activating factor; B-lymphocyte stimulator; BLYS; CD257; D8Ertd387e; delta BAFF; Delta4 BAFF; dendritic cell-derived TNF-like molecule; DTL; RGD1561519; TALL1; TALL-1; THANK; TNF- and APOL-related leukocyte expressed ligand 1; TNF and ApoL-related leukocyte expressed ligand 1; TNF homolog that activates apoptosis; Tnfsf13b; TNFSF20; TNLG7A; tumor necrosis factor (ligand) superfamily member 13 b; tumor necrosis factor (ligand) superfamily, member 13 b; tumor necrosis factor (ligand) superfamily, member 20; tumor necrosis factor ligand 7 A; tumor necrosis factor ligand superfamily member 13 B; Tumor necrosis factor ligand superfamily member 13 b, membrane form; Tumor necrosis factor ligand superfamily member 13 b, soluble form; tumor necrosis factor superfamily member 13 b; tumor necrosis factor-like protein ZTNF4; UNQ401/PRO738; ZTNF4
Nom usuel BAFF (BLyS)
Symbole de gène TNFSF13B
Activité biologique Determined by a mouse splenocyte survival assay. The expected ED50 for this effect is 0.5-2.0 ug/ml
Type de produit Protein
Conjugué Unconjugated
Recombinant Recombinant
Séquence AVQGPEETVT QDCLQLIADS ETPTIQKGSY TFVPWLLSFK RGSALEEKEN KILVKETGYF FIYGQVLYTD KTYAMGHLIQ RKKVHVFGDE LSLVTLFRCI QNMPETLPNN SCYSAGIAKL EEGDELQLAI PRENAQISLD GDVTFFGALK LL
Contenu et stockage -20°C
Activité Determined by a mouse splenocyte survival assay. The expected ED50 for this effect is 0.5-2.0 ug/ml
Système d’expression E. coli
Forme Lyophilized
Grade de qualité ou de pureté ≥ 95% by SDS-PAGE gel and HPLC analyses.
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