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Invitrogen™ Human ALG3 (aa 69-122) Control Fragment Recombinant Protein

Recombinant Protein

Supplier:  Invitrogen™ RP100008

Catalog No. RP100008


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Description

Description

Highest antigen sequence indentity to the following orthologs: Mouse (87%), Rat (87%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60924 (PA5-60924. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

This gene encodes a member of the ALG3 family. The encoded protein catalyzes the addition of the first dol-P-Man derived mannose in an alpha 1,3 linkage to Man5GlcNAc2-PP-Dol. Defects in this gene have been associated with congenital disorder of glycosylation type Id (CDG-Id) characterized by abnormal N-glycosylation. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications

Specifications

Q92685
Blocking Assay, Control
10195
100 μL
ALG3; ALG3, alpha-1,3- mannosyltransferase; asparagine-linked glycosylation 3 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase); asparagine-linked glycosylation 3 homolog (yeast, alpha-1,3-mannosyltransferase); asparagine-linked glycosylation 3, alpha-1,3- mannosyltransferase homolog; asparagine-linked glycosylation protein 3 homolog; carbohydrate deficient glycoprotein syndrome type IV; CDG1D; CDGS4; CDGS6; D16Ertd36e; Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase; dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase; dol-P-Man dependent alpha(1-3)-mannosyltransferase; dol-P-Man dependent alpha-1,3- mannosyltransferase; Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; dol-P-Man:Man(5)GlcNAc(2)-PP-Dol3-mannosyltransferase; dol-P-Man-dependent alpha(1-3)-mannosyltransferase; not; Not56; NOT56L; Not56-like protein
ALG3
Human
His-ABP-tag
-20°C, Avoid Freeze/Thaw Cycles
Liquid
≥5.0 mg/mL
1 M urea, PBS with no preservative; pH 7.4
Human ALG3 (aa 69-122) Control Fragment
RUO
ALG3
Unconjugated
Recombinant
IDWKAYMAEVEGVINGTYDYTQLQGDTGPLVYPAGFVYIFMGLYYATSRGTDIR
E. coli
>80% by SDS-PAGE and Coomassie blue staining
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