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Invitrogen™ HSD17B6 Polyclonal Antibody
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Catalog No. PIPA579406
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100 μg
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Catalog No. Quantity
PIPA579406 100 μg
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Catalog No. PIPA579406 Supplier Invitrogen™ Supplier No. PA579406
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: Human Placenta Tissue, MCF-7 whole cell. IHC: human liver cancer tissue.

The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. Transcript variants utilizing alternative polyadenylation signals exist.

Specifications

Antigen HSD17B6
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
Gene HSD17B6
Gene Accession No. O14756
Gene Alias 17-beta-HSD 6; 17-beta-HSD6; 17betaHSD9; 17-beta-HSD9; 17-beta-hydroxysteroid dehydrogenase type 6; 3(alpha->beta)-hydroxysteroid epimerase; 3(alpha->beta)-hydroxysteroid epimerasel; 3-alpha->beta-HSE; 3-alpha->beta-hydroxysteroid epimerase; 3-hydroxysteroid epimerase; Gm182; Hsd17b6; Hsd17b9; HSE; hydroxysteroid (17-beta) dehydrogenase 6; hydroxysteroid (17-beta) dehydrogenase 6 homolog; hydroxysteroid (17-beta) dehydrogenase 9; hydroxysteroid 17-beta dehydrogenase 6; hydroxysteroid 17-beta dehydrogenase 9; hypothetical protein LOC533086; NAD+ -dependent 3 alpha-hydroxysteroid dehydrogenase 3-hydroxysteroid epimerase; oxidative 17 beta hydroxysteroid dehydrogenase type 6; oxidative 3-alpha hydroxysteroid dehydrogenase; oxidative 3-alpha-hydroxysteroid-dehydrogenase; oxidoreductase; Rdh8; retinol dehydrogenase; RODH; SDR9C6; Short chain dehydrogenase/reductase family 9C member 6; short chain dehydrogenase/reductase family 9C, member 6
Gene Symbols HSD17B6
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human HSD17B6 (300-317aa SLADYILTRSWPKPAQAV).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8630
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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