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ProSci HRSP12 Recombinant Protein

Catalog No. 16594194
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0.05 mg
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16594194 0.05 mg
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Catalog No. 16594194 Supplier ProSci Supplier No. 912360050

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Description

Recombinant Protein

This recombinant protein can be used for biological assays. For research use only.

Heat-Responsive Protein 12 (HRSP12) is an endoribonuclease that belongs to the Rut family. HRSP12 is found mainly in the human adult kidney and liver and is responsible for inhibiting protein translation by cleaving mRNA. HRSP12 only cleaves phosphodiester bonds in single-stranded RNA and inhibits cell-free protein synthesis. The levels of both mRNA and protein are markedly reduced in heptatocellular tumors and in human hepatoma cell lines compared with normal liver tissues. Moreover the levels of HRSP12 are different depending on the grade of the tumor. This had led to the suggestion that HRSP12 may be an important biomarker for heptatic carcinoma.

Specifications

Accession Number P52758
For Use With (Application) Not Available
Gene ID (Entrez) 10247
Molecular Weight (g/mol) 16.7 kDa
Quantity 0.05 mg
Source E. coli
Common Name reactive intermediate imine deaminase A homolog
Gene Symbol RIDA
Product Type Recombinant Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag N-6 His tag
Content And Storage Store at -20°C, stable for 6 months after receipt. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Form Lyophilized
Purity or Quality Grade >95% as determined by reducing SDS-PAGE. Endotoxin level less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
Synonym Ribonuclease UK114, 14.5 kDa Translational Inhibitor Protein, p14.5, Heat-Responsive Protein 12, UK114 Antigen Homolog, HRSP12, PSP
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