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Invitrogen™ HOXB4 Recombinant Rabbit Monoclonal Antibody (23GB6620)
Description
HOXB4 Recombinant Monoclonal Antibody for Flow, ICC/IF, Western Blot
HOX homeobox genes play a role both in the early stem cell function as well as in later stages of hematopoietic differentiation. HOXB4, specifically, is a homeotic selector gene implicated in self-renewal of definitive HSCs. Expression of HOXB4 in primitive progenitors combined with culture on hematopoietic stroma induced a switch to the definitive HSC phenotype. Activation of WNT signaling in HSCs induced increased expression of HOXB4. Perturbations of HOX gene expression can cause leukemia.
Specifications
Specifications
| Antigen | HOXB4 |
| Applications | Flow Cytometry, Western Blot, Immunocytochemistry |
| Classification | Recombinant Monoclonal |
| Clone | 23GB6620 |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | HOXB4 |
| Gene Accession No. | P17483 |
| Gene Alias | homeo box 2F; homeo box B4; homeo box B4a; homeobox B4; homeobox B4a; homeobox gene B-4; homeobox protein Hox-2.6; Homeobox protein Hox-2F; homeobox protein Hox-B4; Homeobox protein Hox-B4a; homeobox protein Zf-13; HOX2; Hox-2.6; HOX2F; Hoxb4; HOX-B4; Hoxb-4; Hoxb4 protein; hoxb4a; Hoxb4a variant 2; RGD1560113; sb:eu512; Z-17; zf13; ZF-13 |
| Gene Symbols | HOXB4 |
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