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Invitrogen™ HLA-F Monoclonal Antibody (3F11F4)
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Catalog No. FERMA548491
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100 μg
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FERMA548491 100 μg
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Catalog No. FERMA548491 Supplier Invitrogen™ Supplier No. MA548491
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Mouse Monoclonal Antibody

HLA-F Monoclonal Antibody for ELISA, Flow, Western Blot

HLA-F belongs to the HLA class I heavy chain paralogues. It is a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Specifications

Antigen HLA-F
Applications ELISA, Flow Cytometry, Western Blot
Classification Monoclonal
Clone 3F11F4
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene HLA-F
Gene Accession No. P30511
Gene Alias CDA12; HLA class I histocompatibility antigen, alpha chain F; HLA class I molecule; HLA F antigen; HLA-5.4; HLA-CDA12; HLAF; HLA-F; Leukocyte antigen F; major histocompatibility complex, class I, F; MHC class I antigen F; MHC class Ib antigen
Gene Symbols HLA-F
Host Species Mouse
Immunogen Purified recombinant fragment of human HLA-F (AA: 22-305) expressed in E. Coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3134
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b
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