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Invitrogen™ HLA-F Monoclonal Antibody (3F11F4)

Description
HLA-F Monoclonal Antibody for ELISA, Flow, Western Blot
HLA-F belongs to the HLA class I heavy chain paralogues. It is a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
Specifications
Specifications
| Antigen | HLA-F |
| Applications | ELISA, Flow Cytometry, Western Blot |
| Classification | Monoclonal |
| Clone | 3F11F4 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.05% sodium azide |
| Gene | HLA-F |
| Gene Accession No. | P30511 |
| Gene Alias | CDA12; HLA class I histocompatibility antigen, alpha chain F; HLA class I molecule; HLA F antigen; HLA-5.4; HLA-CDA12; HLAF; HLA-F; Leukocyte antigen F; major histocompatibility complex, class I, F; MHC class I antigen F; MHC class Ib antigen |
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