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Invitrogen™ HK2 Polyclonal Antibody
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Catalog No. PIPA529326
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100 μL
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Catalog No. Quantity
PIPA529326 100 μL
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Catalog No. PIPA529326 Supplier Invitrogen™ Supplier No. PA529326

Description

Rabbit Polyclonal Antibody

Recommended positive controls: U87-MG, SK-N-SH, IMR32, SK-N-AS, Mouse brain. Predicted reactivity: Mouse (97%), Rat (97%), Zebrafish (86%), Pig (96%), Chicken (88%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III, and IV. Hexokinase activity is involved in the first step in several metabolic pathways including phosphorylation of glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Hexokinase is an allosteric enzyme inhibited by its product GLC-6-P. Hexokinase 2 is the predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Specifications

Antigen HK2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.63 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Hk2
Gene Accession No. A2PYL6, O08528, P27881, P52789
Gene Alias AI642394; DKFZp686M1669; Hexokinase; hexokinase 2; hexokinase II; hexokinase type II; Hexokinase-2; hexokinase-2 muscle; hexokinase-2, muscle; Hexokinase-B; HK II; Hk2; HKII; HXK2; muscle form hexokinase; OTTHUMP00000202738
Gene Symbols Hk2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Hexokinase II. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100009677, 15277, 25059, 3099
Target Species Horse, Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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