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Invitrogen™ HGK Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5106464
Description
Antibody detects endogenous levels of total MAP4K4.
MAP4K4 (HGK) is a serine/threonine kinase which plays an important role in stress-activated MAPK core signaling pathways, the response to environmental stress and cytokines such as TNF-alpha. It appears to act upstream of the JUN N-terminal pathway. This protein is thought to interact with the SH3 domain of the adapter proteins Nck. HGK binds, via its CNH regulatory domain, to the N-terminal region of SPG3A. Expression appears to be ubiquitous, expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain, and isoform 4 is predominant in the liver, skeletal muscle and placenta.Chemical Identifiers
| HGK | |
| -20°C | |
| Polyclonal | |
| Liquid | |
| IgG | |
| Human, Mouse | |
| MAP4K4 | |
| 9430080K19Rik; AU043147; AU045934; AW046177; epididymis secretory protein Li 31; FLH21957; FLJ10410; FLJ20373; FLJ90111; HEL-S-31; hepatocyte progenitor kinase-like/germinal center kinase-like kinase; HGK; HPK/GCK-like kinase HGK; KIAA0687; Map4k4; MAPK/ERK kinase kinase kinase 4; MEK kinase kinase 4; MEKKK 4; MEKKK4; mitogen activated protein kinase kinase kinase kinase 4; mitogen-activated protein kinase kinase kinase kinase 4; NCK interacting kinase; nck-interacting kinase; NIK; Ste20 group protein kinase HGK | |
| MAP4K4 | |
| Primary | |
| Affinity chromatography |
| 1 mg/mL | |
| Western Blot, Immunocytochemistry | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| O95819, P97820 | |
| 26921, 9448 | |
| A synthesized peptide derived from human MAP4K4(Accession O95819), corresponding to amino acid residues E410-R460. | |
| Antibody |
Specifications
| HGK | |
| Polyclonal | |
| Unconjugated | |
| MAP4K4 | |
| 9430080K19Rik; AU043147; AU045934; AW046177; epididymis secretory protein Li 31; FLH21957; FLJ10410; FLJ20373; FLJ90111; HEL-S-31; hepatocyte progenitor kinase-like/germinal center kinase-like kinase; HGK; HPK/GCK-like kinase HGK; KIAA0687; Map4k4; MAPK/ERK kinase kinase kinase 4; MEK kinase kinase 4; MEKKK 4; MEKKK4; mitogen activated protein kinase kinase kinase kinase 4; mitogen-activated protein kinase kinase kinase kinase 4; NCK interacting kinase; nck-interacting kinase; NIK; Ste20 group protein kinase HGK | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 26921, 9448 | |
| -20°C | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| O95819, P97820 | |
| MAP4K4 | |
| A synthesized peptide derived from human MAP4K4(Accession O95819), corresponding to amino acid residues E410-R460. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |