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Invitrogen™ HGK Monoclonal Antibody (4H9E7)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA515422
Description
MA5-15422 targets MAP4K4 in indirect ELISA, WB applications and shows reactivity with Human samples. The MA5-15422 immunogen is purified recombinant fragment of MAP4K4 (aa400-500) expressed in E. Coli.
MAP4K4 (HGK) is a serine/threonine kinase which plays an important role in stress-activated MAPK core signaling pathways, the response to environmental stress and cytokines such as TNF-alpha. It appears to act upstream of the JUN N-terminal pathway. This protein is thought to interact with the SH3 domain of the adapter proteins Nck. HGK binds, via its CNH regulatory domain, to the N-terminal region of SPG3A. Expression appears to be ubiquitous, expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain, and isoform 4 is predominant in the liver, skeletal muscle and placenta.Chemical Identifiers
| HGK | |
| Conc. Not Determined | |
| ELISA, Western Blot | |
| Unconjugated | |
| Mouse | |
| RUO | |
| ascites with 0.03% sodium azide | |
| O95819 | |
| 9448 | |
| Purified recombinant fragment of MAP4K4 (aa400-500) expressed in E. Coli. | |
| Antibody |
| 4H9E7 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Monoclonal | |
| Liquid | |
| IgG1 | |
| Human | |
| MAP4K4 | |
| 9430080K19Rik; AU043147; AU045934; AW046177; epididymis secretory protein Li 31; FLH21957; FLJ10410; FLJ20373; FLJ90111; HEL-S-31; hepatocyte progenitor kinase-like/germinal center kinase-like kinase; HGK; HPK/GCK-like kinase HGK; KIAA0687; Map4k4; MAPK/ERK kinase kinase kinase 4; MEK kinase kinase 4; MEKKK 4; MEKKK4; mitogen activated protein kinase kinase kinase kinase 4; mitogen-activated protein kinase kinase kinase kinase 4; NCK interacting kinase; nck-interacting kinase; NIK; Ste20 group protein kinase HGK | |
| MAP4K4 | |
| Primary |
Specifications
| HGK | |
| Monoclonal | |
| Conc. Not Determined | |
| ascites with 0.03% sodium azide | |
| O95819 | |
| MAP4K4 | |
| Purified recombinant fragment of MAP4K4 (aa400-500) expressed in E. Coli. | |
| RUO | |
| 9448 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| ELISA, Western Blot | |
| 4H9E7 | |
| Unconjugated | |
| MAP4K4 | |
| 9430080K19Rik; AU043147; AU045934; AW046177; epididymis secretory protein Li 31; FLH21957; FLJ10410; FLJ20373; FLJ90111; HEL-S-31; hepatocyte progenitor kinase-like/germinal center kinase-like kinase; HGK; HPK/GCK-like kinase HGK; KIAA0687; Map4k4; MAPK/ERK kinase kinase kinase 4; MEK kinase kinase 4; MEKKK 4; MEKKK4; mitogen activated protein kinase kinase kinase kinase 4; mitogen-activated protein kinase kinase kinase kinase 4; NCK interacting kinase; nck-interacting kinase; NIK; Ste20 group protein kinase HGK | |
| Mouse | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |