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Invitrogen™ Hemoglobin alpha Polyclonal Antibody
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Catalog No. PIPA579347
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100 μg
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Catalog No. Quantity
PIPA579347 100 μg
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Catalog No. PIPA579347 Supplier Invitrogen™ Supplier No. PA579347

Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.

Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human placenta tissue. IHC: human placenta tissue, human tonsil tissue. Flow: K562 cell.

The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.

Specifications

Antigen Hemoglobin alpha
Applications Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and no preservative
Gene Hba1
Gene Accession No. P69905
Gene Alias alpha 1 globin; alpha globin 1; alpha one globin; alpha-1/2-globin; alpha-2 globin chain; alpha-globin; delta globin; GloA; globin, alpha; haemaglobin alpha 1; Hba; HBA1; HBA2; Hba-a1; Hba-a2; HBAM; Hbat1; HBA-T3; HBH; hemoglobin alpha 1 chain; hemoglobin alpha 1 globin chain; hemoglobin alpha chain; hemoglobin alpha, adult chain 1; hemoglobin alpha, adult chain 2; hemoglobin alpha-1/2 chain; Hemoglobin subunit alpha; hemoglobin subunit alpha 1; hemoglobin subunit alpha-1/2; hemoglobin, alpha 1; LOC287167
Gene Symbols Hba1
Host Species Rabbit
Immunogen E.coli-derived human Hemoglobin recombinant protein (Position: V2-R142).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3039
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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