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Gibco™ Heat Stable FGF-10 Recombinant Protein 
Recombinant Protein
Supplier: Gibco™ PHG0371
Description
FGF10 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This protein is also implicated to be a primary factor in the process of wound healing.Specifications
| O15520 | |
| protein with 20 mM Na2PO4, 750 mM NaCl and no preservative; pH 7.5 | |
| Heat Stable FGF-10 | |
| 5 μg | |
| AEY17; BB213776; FGF; Fgf10; FGF-10; Fibroblast growth factor; Fibroblast growth factor 10; Gsfaey17; Keratinocyte growth factor 2; produced by fibroblasts of urinary bladder lamina propria | |
| ED50 = 1.0 ng/mL; measured in a cell proliferation assay using 4 MBr-5 cells | |
| Unconjugated | |
| Recombinant | |
| 750 mM NaCl, 20 mM Na2PO4 | |
| Recombinant | |
| E. coli | |
| >95% by SDS-PAGE |
| Functional Assay | |
| 2255 | |
| SDS-Page | |
| 0.25 EU/μg | |
| FGF10 | |
| Protein | |
| Human | |
| Thermostable variant of human FGF-10 (190 amino acids) with proprietary amino acid substitutions | |
| -20°Cor to +80°C if preferred | |
| ED50 ≤1.0 ng/mL; measured in a cell proliferation assay using 4 MBr-5 cells | |
| Lyophilized |