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Invitrogen™ H4ac pan-acetyl (K5,K8,K12,K16) Recombinant Mouse Monoclonal Antibody (KM-2)
Mouse Recombinant Monoclonal Antibody
Supplier: Invitrogen™ MA551790
Description
KM-2 antibody recognizes the N-terminal peptides 1-20 of histone H2A and 1-29 of histone H4 which have a large sequence homology. Histone H4 acetylation on lysines 8, 12 and 16 significantly increases the antibody's binding while the acetylation at K5 decreases it.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.Chemical Identifiers
| H4ac pan-acetyl (K5,K8,K12,K16) | |
| 1 mg/mL | |
| ELISA, Immunohistochemistry, Western Blot, Immunocytochemistry | |
| Unconjugated | |
| Mouse | |
| RUO | |
| PBS with 0.02% ProClin 300 | |
| P62805 | |
| 121504, 8294, 8359, 8363, 8366, 8367, 8370 | |
| KM-2 antibody was derived from an MRL/lpr lupus mouse. | |
| Antibody |
| KM-2 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Recombinant Monoclonal | |
| Liquid | |
| IgG2a κ | |
| Human | |
| H4C1 | |
| acetyl Histone H4; Acetyl-H4 K5 K8 K12 K16; Acetyl-H4 Lys5 Lys8 Lys12 Lys16; Acetyl-Histone H4 K5 K8 K12 K16; Acetyl-Histone H4 Lys5 Lys8 Lys12 Lys16; FO108; H4; H4 ac pan-acetyl; H4 histone family, member A; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/J; H4/K; H4/M; H4/n; H4/O; H4/p; H4-12; H4-16; H4-53; H4ac; H4c1; H4c11; H4C12; H4C13; H4c14; H4C15; H4c2; H4c3; H4c4; H4C5; H4c6; H4C8; H4c9; H4f16; H4F2; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4K12; H4K12a; H4K12ac; H4K16; H4K16ac; H4K5; H4K5,8,12,16ac; H4K5ac; H4K8; H4K8ac; H4Lys5,8,12,16ac; H4M; HIST1H4; HIST1H4A; Hist1h4b; HIST1H4C; Hist1h4d; HIST1H4E; Hist1h4f; Hist1h4h; Hist1h4i; HIST1H4J; Hist1h4k; HIST1H4L; Hist1h4m; Hist2h4; HIST2H4A; HIST2H4B; Hist4h4; histone 1, H4a; histone 1, H4b; histone 1, H4e; histone 1, H4i; histone 2, H4; histone 2, H4a; Histone 4; Histone 4 family, member M; histone 4, H4; histone cluster 1, H4a; histone cluster 1, H4b; histone cluster 1, H4e; histone cluster 1, H4i; histone cluster 2, H4; histone cluster 2, H4a; Histone Cluster 4; histone cluster 4, H4; histone family member; histone H4; Histone H4 acetyl; Histone H4A; Histone H4K12; Histone H4K16; Histone H4K5; Histone H4K8; histone IV, family 2; X04652 | |
| H4-16, H4C1, H4C11, H4C14, H4C2, H4C5, H4C9 | |
| Primary | |
| Protein A |
Specifications
| H4ac pan-acetyl (K5,K8,K12,K16) | |
| Recombinant Monoclonal | |
| 1 mg/mL | |
| PBS with 0.02% ProClin 300 | |
| P62805 | |
| H4-16, H4C1, H4C11, H4C14, H4C2, H4C5, H4C9 | |
| KM-2 antibody was derived from an MRL/lpr lupus mouse. | |
| 200 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2a κ |
| ELISA, Immunohistochemistry, Western Blot, Immunocytochemistry | |
| KM-2 | |
| Unconjugated | |
| H4C1 | |
| acetyl Histone H4; Acetyl-H4 K5 K8 K12 K16; Acetyl-H4 Lys5 Lys8 Lys12 Lys16; Acetyl-Histone H4 K5 K8 K12 K16; Acetyl-Histone H4 Lys5 Lys8 Lys12 Lys16; FO108; H4; H4 ac pan-acetyl; H4 histone family, member A; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/J; H4/K; H4/M; H4/n; H4/O; H4/p; H4-12; H4-16; H4-53; H4ac; H4c1; H4c11; H4C12; H4C13; H4c14; H4C15; H4c2; H4c3; H4c4; H4C5; H4c6; H4C8; H4c9; H4f16; H4F2; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4K12; H4K12a; H4K12ac; H4K16; H4K16ac; H4K5; H4K5,8,12,16ac; H4K5ac; H4K8; H4K8ac; H4Lys5,8,12,16ac; H4M; HIST1H4; HIST1H4A; Hist1h4b; HIST1H4C; Hist1h4d; HIST1H4E; Hist1h4f; Hist1h4h; Hist1h4i; HIST1H4J; Hist1h4k; HIST1H4L; Hist1h4m; Hist2h4; HIST2H4A; HIST2H4B; Hist4h4; histone 1, H4a; histone 1, H4b; histone 1, H4e; histone 1, H4i; histone 2, H4; histone 2, H4a; Histone 4; Histone 4 family, member M; histone 4, H4; histone cluster 1, H4a; histone cluster 1, H4b; histone cluster 1, H4e; histone cluster 1, H4i; histone cluster 2, H4; histone cluster 2, H4a; Histone Cluster 4; histone cluster 4, H4; histone family member; histone H4; Histone H4 acetyl; Histone H4A; Histone H4K12; Histone H4K16; Histone H4K5; Histone H4K8; histone IV, family 2; X04652 | |
| Mouse | |
| Protein A | |
| RUO | |
| 121504, 8294, 8359, 8363, 8366, 8367, 8370 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |