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  6. Invitrogen™ GTF2E1 Recombinant Rabbit Monoclonal Antibody (23GB6310)

Invitrogen™ GTF2E1 Recombinant Rabbit Monoclonal Antibody (23GB6310)
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Catalog No. p-200056614
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100 μL
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MA553018 100 μL
MA553019 20 μL
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Description

Rabbit Recombinant Monoclonal Antibody

GTF2E1 Recombinant Monoclonal Antibody for Flow, ICC/IF, Western Blot

The general transcription factor TFIIE has an essential role in eukaryotic transcription initiation together with RNA polymerase II and other general factors. Human TFIIE consists of two subunits of relative molecular mass 57, 000 (TFIIE-alpha) and 34, 000 (TFIIE-beta) and joins the preinitiation complex after RNA polymerase II and TFIIF. TFIIE-alpha is necessary for transcription initiation together with TFIIE-beta, and recombinant TFIIE-alpha can fully replace the natural subunit in an in vitro transcription assay. Its sequence contains several interesting structural motifs (leucine repeat, zinc finger and helix-turn-helix) and sequence similarities to bacterial sigma factors that suggest direct involvement in the regulation of transcription initiation.

Specifications

Antigen GTF2E1
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 23GB6310
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene GTF2E1
Gene Accession No. P29083, Q9D0D5
Gene Alias 2610024P03Rik; 56kDa; AI303800; FE; general transcription factor II E, polypeptide 1 (alpha subunit); general transcription factor II E, polypeptide 1 (alpha subunit, 56kDa); general transcription factor IIE 56 kDa subunit; General transcription factor IIE subunit 1; General transcription factor IIE subunit 1-like protein; general transcription factor IIE, polypeptide 1 (alpha subunit); general transcription factor IIE, polypeptide 1 (alpha subunit, 56kDa); general transcription factor IIE, polypeptide 1, alpha; general transcription factor IIE, polypeptide 1, alpha 56kDa; GTF2E1; TF2E1; TFIIE alpha subunit; TFIIE-A; TFIIE-alpha; Transcription initiation factor IIE subunit alpha
Gene Symbols GTF2E1
Host Species Rabbit
Immunogen A synthesized peptide derived from human TFIIE alpha (400-439AA).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2960, 303918, 74197
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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