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Invitrogen™ GSK3B Recombinant Rabbit Monoclonal Antibody (23GB1250)
Description
GSK3B Recombinant Monoclonal Antibody for Flow, ICC/IF, Western Blot
GSK3B is a proline-directed serine/threonine protein kinase involved in energy metabolism, neuronal cell development and body pattern formation. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. GSK3B is a critical component of the Wnt/beta-catenin signaling pathway, and its activity results in the inhibition of Wnt signaling by mediating the degradation of beta-catenin. GSK3B is also involved in the Hedgehog, Notch, and insulin signaling pathways.
Specifications
Specifications
| Antigen | GSK3B |
| Applications | Flow Cytometry, Western Blot, Immunocytochemistry |
| Classification | Recombinant Monoclonal |
| Clone | 23GB1250 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | GSK3B |
| Gene Accession No. | P18266, P49841, Q9WV60 |
| Gene Alias | 7330414F15Rik; 8430431H08Rik; C86142; EC 2.7.11.26; FA; Factor A; fb68h05; fk80d11; glycogen synthase kinase 3; glycogen synthase kinase 3 beta; glycogen synthase kinase 3 beta L homeolog; glycogen synthase kinase 3 beta variant 1; glycogen synthase kinase 3 beta variant 2; glycogen synthase kinase 3 beta variant 3; glycogen synthase kinase 3 beta variant 4; glycogen synthase kinase 3 beta variant 5; glycogen synthase kinase 3 beta, genome duplicate a; glycogen synthase kinase-3 beta; glycogen synthase kinase-3 beta splice variant X1; glycogen synthase kinase-3 beta splice variant X2; glycogen synthase kinase-3 beta splice variant X3; GSK 3 beta; GSK 3B; gsk3; GSK-3; GSK3 beta; GSK-3 beta; GSK-3 beta GSK3B; GSK-3[b]; Gsk3b; GSK-3b; gsk3b.L; gsk3ba; gsk3beta; GSK-3beta; gsk3-beta; GSK3beta isoform; intracellular kinase; pp37; serine/threonine-protein kinase GSK3B; wu:fb68h05; wu:fk80d11; XELAEV_180112401mg; xgsk-3; Xgsk-3 protein |
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