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Invitrogen™ GRPR Recombinant Rabbit Monoclonal Antibody (18H31L38) 
Rabbit Recombinant Monoclonal Antibody
Supplier: Invitrogen™ 703928
Description
This antibody is predicted to react with Mouse, Rat, Bovine.
Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.Specifications
| GRPR | |
| Recombinant Monoclonal | |
| 0.5 mg/mL | |
| PBS with 0.09% sodium azide; pH 7.4 | |
| P30550 | |
| GRPR | |
| Peptides corresponding to human GRPR [aa364-aa384, aa4-aa19]. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
| Immunohistochemistry, Immunocytochemistry | |
| 18H31L38 | |
| Unconjugated | |
| GRPR | |
| BB2; BB2R; bombesin receptor 2; gastrin releasing peptide receptor; gastrin-releasing peptide receptor; GRP receptor; GRP-preferring bombesin receptor; GRPR; GRP-R | |
| Rabbit | |
| Protein A | |
| RUO | |
| 2925 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |