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Invitrogen™ GPS2 Polyclonal Antibody
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Catalog No. PIPA576547
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100 μL
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Catalog No. Quantity
PIPA576547 100 μL
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Catalog No. PIPA576547 Supplier Invitrogen™ Supplier No. PA576547
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.

Specifications

Antigen GPS2
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene GPS2
Gene Accession No. Q13227, Q921N8
Gene Alias AI505953; AMF-1; G protein pathway suppressor 2; GPS2; GPS-2
Gene Symbols GPS2
Host Species Rabbit
Immunogen Synthetic peptide of mouse GPS2.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2874, 497941, 56310
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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