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Invitrogen™ GPR77 Recombinant Rabbit Monoclonal Antibody (HL4182)

Description
GPR77 Recombinant Monoclonal Antibody for Western Blot
C5AR2 is an orphan member that belongs to anaphylatoxin receptor family. It is a seven transmembrane G-protein-coupled receptor consisting of an N-terminal N-glycosylation site, several conserved cysteines and several potential C-terminal phosphorylation sites. It binds to C5a and C5a-des-Arg and serves as a highly regulated scavenger receptor with a negative modulatory influence on C5aR-mediated inflammation. Northern Blot analysis suggests it is co- expressed along with C5aR in different tissues and cells including neutrophils/macrophages, mast cells, dendritic cells, brain, lung, heart, kidney, liver, ovary and testis.
Specifications
Specifications
| Antigen | GPR77 |
| Applications | Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | HL4182 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with no preservative |
| Gene | C5AR2 |
| Gene Accession No. | Q9P296 |
| Gene Alias | C5a anaphylatoxin chemotactic receptor 2, C5a anaphylatoxin chemotactic receptor C5L2, C5AR2, C5L2, Complement component 5a receptor 2, G protein-coupled receptor 77, G protein-coupled receptor C5L2, GPF77, GPR77, G-protein coupled receptor 77 |
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