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  6. Invitrogen™ GPCR/G-protein complex-stabilizing scFv Recombinant Mouse Monoclonal Antibody (scFv16)

Invitrogen™ GPCR/G-protein complex-stabilizing scFv Recombinant Mouse Monoclonal Antibody (scFv16)

Catalog No. 7039761MG
Encompass
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100 μg
1 mg
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7039761MG 1 mg
703976 100 μg
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Catalog No. 7039761MG Supplier Invitrogen™ Supplier No. 7039761MG

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Description

Mouse Recombinant Monoclonal Antibody

The scFv antibody stabilizes GPCR/G-protein complexes for cryo-EM of active structures. It recognizes an interface between G alpha and G beta/gamma subunits, and confers resistance to nucleotide exchange-triggered dissociation of the heterotrimeric G-protein. In addition to members of the Gi/o family, this antibody fragment can also be applied to chimeric variants and stabilize other G-protein subtypes including Gs complexes.

Specifications

Antigen GPCR/G-protein complex-stabilizing scFv
Applications Not Available
Classification Recombinant Monoclonal
Clone scFv16
Concentration 2.0 mg/mL
Conjugate Unconjugated
Formulation 25mM HEPES with 10% glycerol and no preservative; pH 7.5
Host Species Mouse
Immunogen Rhodopsin/Gi1.
Purification Method Affinity chromatography
Quantity 1 mg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
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